Application Industry | Application Project |
Biological Engineering | Vaccines (human meningococcal vaccines, conjugate polysaccharide vaccines/veterinary VERO cells, insect cells, 293 cells), protein therapeutics (E. coli, yeast cells: norovirus, HPV vaccines), diagnostic reagent raw materials (IVD), enzyme engineering, etc. |
Pharmaceutical preparations | Fat emulsions, liposomes, lipid nanoparticles, suspensions, etc. |
Food Emulsification | Juice, milk, functional beverages, food additives, flavorings, etc. |
Cosmetics | Liposome cosmetics, creams, lotions, sodium hyaluronate, coenzyme Q10, etc. |
Fine Chemicals | Nano-cellulose, polymer materials, ink, nano-fuel, materials, etc. |
I. Principle Overview
The high-pressure homogenizer employs a reciprocating plunger pump to draw samples through a single-phase valve into the high-pressure pump head. The sample is then forced into a narrow gap (the homogenizing valve). As particles pass through this valve, they undergo extreme compression at pressures as high as 1000 bar. Upon exiting the valve, the particles return to atmospheric pressure. This instantaneous pressure release achieves uniform and fine particle refinement. Generally, a greater pressure differential yields superior homogenization. During this process, the extreme velocity and unique trajectory generate explosive forces alongside immense shear and impact forces, collectively achieving excellent homogenization of the sample.
In summary, the homogenizing effect of the homogenizer primarily stems from three internal mechanisms: cavitation effect, shear effect, and impact effect.
II. Product Features
1. Product Application: Food emulsification, etc.
2. Feed Product Viscosity: ≤20,000 cP
3. Maximum Feed Particle Size: ≤500 μm
4. Maximum Feed Temperature: ≤90°C
5. Homogenizing handle stage: Single-stage homogenization
6. Maximum Design Pressure: 1800 bar / 180 MPa
7. Maximum Operating Pressure: 1500 bar / 150 MPa
8. Pressure Sensor Range: 0-2000 bar
9. Equipment Processing Capacity: 3-16 L/H (adjustable flow rate)
10. Minimum Sample Processing Volume: 15 ml
11. High-pressure pump head pressure detection type: High-precision pressure sensor + touchscreen display
12. Equipment temperature control method: External cooling
13. Power drive method: Motor-driven, crankshaft box employs crankshaft-connecting rod transmission structure for enhanced operational stability
14. Main motor parameters: 1.5 kW/8-pole IP55
15. Equipment power requirements: 220V/50Hz
16. Plunger Type: Sanitary (ceramic construction)
17. Plunger Quantity: 1
18. High-Pressure Module Material: Forged medical-grade SUS316L or SAF2205 stainless steel
19. Power End Cooling: Fan cooling
20. Feed Connection Method: Tri-Clamp quick connection
21. Homogenizer Valve Material: Stellite hard alloy (optional diamond valve core/seat and Stellite hard alloy impact ring)
22. Maximum Cleaning Temperature: ≤90°C
23. Maximum Sterilization Temperature: ≤145°C (Standard configuration unsuitable; requires customization)
24. Cleaning/Sterilization Time: ≤30 minutes
III. Core Component Description:
• Core Pressure Module: Split-type structure forged from SAF2205 ultra-high hardness special stainless steel, undergoes solution treatment and ultrasonic flaw detection, then heat-treated and machined.
• Plunger Rod: Fully ceramic construction with surface finish within 0.01 microns, reducing wear on plunger seals and extending seal lifespan. Features high abrasion resistance and is reversible for use on either end.
• Plunger Seal: Manufactured from Italian-imported ultra-high molecular weight composite material, offering exceptional pressure resistance and self-lubricating properties.
• Pressure Adjustment Handle: Utilizes Italian ELESA components with ergonomic design, enabling manual pressure increase and decrease.
• Handle Pressure Adjustment Spring: Features German Moebel springs with high elasticity and extended service life.
• Homogenizer Valve Assembly: Constructed from U.S.-imported materials, featuring highly wear-resistant diamond and special hard alloy components. Dual-sided design doubles the service life of the homogenizer valve.
• Pressure Sensor: Custom high-precision pressure sensor with a measurement range of 0~2000 bar. Measurement accuracy to 1 bar, sensor precision 0.5% FS.
• Main Motor: ABB 1.5 kW, 8-pole high-power motor ensures stable operation under high pressure.
• Heavy-Duty Bearings: Power-end heavy-duty bearings utilize Swedish SKF components.
• Variable Frequency Flow System: Bosch flow controller enables precise regulation of equipment flow rates.
• Transmission System: Imported belt drive with synchronous pulley reduction design.
• Feed valve seat: Custom-made from Stellite alloy (diamond material available upon request).
• Material temperature control system: External cooling system.
• Power transmission system: Crankshaft-connecting rod structure with closed-bearing connection between crankshaft and piston, ensuring stable long-term operation under high pressure.
• Power-End Lubrication: Liquid lubricant ensures thorough lubrication during transmission, extending power-end service life.
• Safety Protection System: Customizable safety pressure thresholds automatically halt operation when average pressure exceeds set limits, preventing damage from sudden pressure surges.
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