In the field of biopharmaceuticals, many therapeutic proteins, enzymes, antibodies, and vaccines, which are biological products, have poor stability in liquid form and are prone to degradation or inactivation. Vacuum freeze-drying technology, by sublimating moisture at low temperatures, can help achieve long-term stable storage of protein drugs, which is a key technology to ensure their shelf life, transportation safety, and clinical efficacy. This program elaborates on the specialized freeze-drying solutions for protein drugs.

1. Core of the plan: From “stability” to “long-term effectiveness”

The core goal of this program is to help address two major challenges in protein drugs:

1.      Liquid instability: includes chemical degradation (such as deamidation, oxidation) and physical denaturation (such as aggregation, precipitation).

2.     Long-term storage and transportation: Liquid formulations often require harsh cold chain conditions, while lyophilized powder injectables can achieve long-term stable storage at room temperature or 2-8℃.

The core value of vacuum freeze-drying technology in this link lies in its precise low-temperature dehydration process, which helps to improve the retention of natural spatial conformation and biological activity of proteins, thus contributing to the safety and effectiveness of drugs.